Jeffrey L Carson, MD
Principal Investigator and Study Chairman
Clinical Coordinating Center
Richard C Reynolds Professor of Medicine
Chief, Division of General Internal Medicine
Dr. Jeffrey Carson is Richard C. Reynolds Professor of Medicine, and Chief, Division of General Internal Medicine at the UMDNJ-Robert Wood Johnson Medical School and is principal investigator and study chairman of FOCUS. Dr. Carson is a board-certified internist and his practice includes the care of pre- and post-operative surgical patients.
Dr. Carson received his initial research training during a two-year
Henry J. Kaiser Fellowship at the University of Pennsylvania. He
was a member of the Epidemiology and Disease Control - 1 Study
Section at NIH from 1990-1994 and served as an Ad-hoc reviewer
for AHCPR and NIH. He received additional research training specifically
in the area of clinical trials as a Fogarty Senior International
Fellow at the University of Oxford, England from September 1995-June
Carson’s research in blood transfusion began over 17 years
ago with the initiation of a cohort study of 125 Jehovah Witness
patients undergoing surgery. He was the principal investigator
on the NHLBI supported study of anemia and surgery in 1,958 Jehovah
Witness patients and the Agency for Health Care Policy and Research
funded study on Surgical Blood Transfusion. Dr. Carson administered
this large (10,000 patient) multi-center study involving 20 hospitals.
He is also the lead investigator on a number of industry sponsored
Dr. Carson has published over 125 peer reviewed papers,
book chapters, and editorials. He has been
awarded 5 teaching awards including the 2002
Alpha Omega Alpha Faculty Recognition Award. He has been on the
Best Doctors list for many years.
Michael L. Terrin, M.D., C.M., M.P H..
Principal Investigator, Data Coordinating Center
Professor of Epidemiology and Preventive Medicine
University of Maryland
Dr. Michael Terrin, an internist with subspeciality certification in pulmonary disease, and an MPH in epidemiology, will serve as Principal Investigator and Director of the Data Coordinating Center (DCC). His is Professor of Epidemiology and Preventive Medicine at the University of Maryland. He has been the Principal Investigator of the Medical Coordinating Center for the Multicenter Study of Hydroxyurea in Sickle Cell Anemia (MSH) Patients’ Follow-Up, for the Phase III Pediatric Hydroxyuria (BABYHUG) clinical trial, for the Coordinating Center of the Randomized Study of the Efficacy of Physician Extender-Assisted, Protocolized Care in Heart Failure Outpatients at High Risk for Hospital Readmission (CHF) Team Study and the Interim Analysis Center for the Study of Post-Menopausal Hormone Therapy for Unstable Angina (PMHT), and Co-Principal Investigator for the ACCESS Clinical Coordinating Center. He was Principal Investigator of the Data Coordinating Center for the Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED), the Data Coordinating Center for the Multicenter Study of Hydroxyurea in Sickle Cell Anemia (MSH), for the Ursodeoxycholic Acid in the Treatment of Cystic Fibrosis Associated Liver Disease (URSO) Study, Deputy Director for the TIMI I and TIMI II Coordinating Centers, for the HA-1A Study Randomization, Allocation and Interim Analysis Center, for the POST CABG Studies Coordinating Center and Deputy Director for the ACIP and PIMI Clinical Coordinating Centers. Prior to joining MMRI in 1982, he held a cardiovascular epidemiology training grant at the Johns Hopkins University School of Hygiene and Public Health. Dr. Terrin and Dr. Carson have worked together in research for more than 15 years from PIOPED to FOCUS.